Isabella d'Este (Modena, October 3 1635 - Colorno, August 21 1666), was Duchess of Parma, and second wife of Duke Ranuccio II Farnese. Isabella was a daughter of the Duke of Modena Francesco I d'Este and Maria Caterina Farnese, daughter of Ranuccio I Farnese, Duke of Parma. After the death of his first wife Marguerite of Savoy, Ranuccio II married in 1663 his niece Isabella. But the couple only met on February 18 1664, when Isabella arrived in Parma. Wikipedia
The definitive Wikipedia entry for Isabella Of Modena. Wikipedia is the biggest multilingual free-content encyclopedia on the Internet. en.wikipedia.org/wiki/Isabella_of_Modena