Edward Moore "Ted" Kennedy (born February 22, 1932) is the senior United States Senator from Massachusetts and a member of the Democratic Party. In office since November 1962, Kennedy is presently the second-longest serving member of the Senate, after Robert Byrd of West Virginia. The most prominent living member of the Kennedy family, he is the younger brother of President John F. Kennedy and Senator Robert F. Kennedy, both of whom were assassinated in the 1960s.

Hamilton Fish III (born Hamilton Stuyvesant Fish and also known as Hamilton Fish, Jr.); December 7, 1888 - January 18, 1991 was a soldier and politician from New York. Born into a family long active in the politics of New York, …

Matthew Robert Birk (born July 23 1976) is a professional American football player (center) for the NFL's Minnesota Vikings franchise since being drafted by them out of Harvard University. Birk has made multiple Pro Bowls since replacing Jeff Christy, who left the Vikings in 2000.

Endicott "Chub" Peabody (February 15, 1920-December 1, 1997) was Governor of Massachusetts from January 3, 1963 to January 7, 1965. Peabody was born in Lawrence, Massachusetts, served in the United States Navy during World War II, and received a BA and a law degree from Harvard University. He was admitted to the Massachusetts bar on October 14, 1948. A star defensive lineman for the Harvard football team, he was later inducted into the College Football Hall of Fame.

Clifton Dawson (born October 8 1983) is a Canadian professional football running back for the Indianapolis Colts of the NFL and formerly for Harvard University. He is the all-time Ivy League career rushing leader with 4,841 yards. He was selected four times for 1st Team All-Ivy League. He is also the 8th player in NCAA Division I history to rush for over 1,000 yards a season 4 times. Dawson briefly attended Northwestern University before opting to transfer to Harvard.

Tommy Lee Jones (born September 15, 1946) is an Academy Award-winning American actor and director.

John Dockery is a sportscaster and former New York Jets player in the American Football League in 1968 and 1969. He was drafted by the Jets out of Harvard. He also played in the NFL after 1969, for the Jets and the Steelers. Following his retirement, Dockery went on to co-host "Sports Extra" on WNYW Channel 5 in New York City with Bill Mazer. Dockery currently works on "The NFL on Westwood One" as their "Monday Night Football" sideline reporter.

Patrick John "Pat" McInally (born May 7, 1953 in Villa Park, California), is a former punter and wide receiver for the National Football League's Cincinnati Bengals from 1976 to 1985. He attended Harvard University and was drafted in the 5th round of the 1975 NFL draft. He wore uniform #87. Due to a broken leg he suffered in the College All-Star Game at the hands of the Pittsburgh Steelers (who are still the Bengals' division rivals), McInally missed his entire rookie year.

Ryan Joseph Fitzpatrick is an NFL quarterback for the Saint Louis Rams, and was a star for the Harvard University Crimson. Fitzpatrick was drafted in the 7th round of the 2005 NFL Draft. He was 15–1 in his last two seasons at Harvard. Fitzpatrick's 384 completed passes, 39 touchdowns, 5,234 yards passing, and 59.9 percent pass completion percentage are each second in Harvard's history, surpassed only by his predecessor, Neil Rose.

Danny Jiggetts (born March 10, 1954 in Brooklyn, New York) is a retired American football offensive lineman. He was drafted by the Chicago Bears in the 1976 NFL Draft

Isaiah J. Kacyvenski (born October 3 1977) is an NFL outside linebacker with the Oakland Raiders.

Paul DePodesta (born December 16, 1972) is baseball front-office assistant for the San Diego Padres. He has also served as general manager of the Los Angeles Dodgers from February 16, 2004 to October 29, 2005. He was the ninth general manager in the club's history since moving to Los Angeles. He is a native of Alexandria, Virginia and attended Harvard University, where he played baseball and football and graduated cum laude in 1995 with a degree in economics.

Frank T. Caprio (born May 10, 1966) is the General Treasurer of Rhode Island. He was the first political candidate in United States to use On-Demand television to reach voters and one of the first candidates to launch an internet TV channel for use in a political campaign in 2006. Frank T. Caprio is the eldest child of Joyce and Judge Frank Caprio, and he is the brother of Rhode Island State Representative David Caprio.