- John Cooper
John Cooper (born July 2, 1937 in Knoxville, Tennessee) was the head coach of the Ohio State Buckeyes college football team from 1988 to 2000. Cooper grew up in the Knoxville suburb of Powell, Tennessee and joined the United States Army after high school. After serving for two years, he enrolled at Iowa State University where he played football for four years eventually becoming team captain and MVP. Cooper spent time as an assistant coach at Iowa State, Oregon State, UCLA, …
- Jack Trice
Johnny (Jack) Trice (born, Hiram, Ohio, 1902 - died, Ames, Iowa, October 8, 1923) was an African-American football player from Iowa State College (now Iowa State University), who died due to injuries suffered during a college football game against the University of Minnesota on October 6, 1923. Many suspected the injuries inflicted were racially motivated. Trice's death paralleled that of an on-field assault against an African-American, Drake University football player, …
- Larry Carwell
Larry Carwell was an American college and professional football player. A cornerback, he played college football at Iowa State University, and played professionally in the American Football League for the Houston Oilers in 1967 and 1968 and the Boston Patriots in 1969. He continued to play for the NFL Boston Patriots and later the NFL New England Patriots from 1970 through 1972.
- Joe Beauchamp
Joe Beauchamp was an American college and professional football player. A defensive back, he played college football at Iowa State University, and played professionally in the American Football League for the San Diego Chargers from 1966 through 1969, and for the Chargers in the NFL from 1970 through 1975.
- Matt Blair
Matt Blair (born September 20, 1950) was a linebacker for the Minnesota Vikings of the National Football League for 12 seasons from 1974-1985. Blair was selected out of Iowa State University by the Vikings in the second round of the 1974 NFL Draft with the 51st overall selection. Blair established himself as one of the top linebackers in the NFC during the prime of his career, earning Pro Bowl honors for 6 consecutive seasons (1977-'82).
- Sage Rosenfels
Sage Rosenfels (born March 6, 1978 in Maquoketa, Iowa) is an American football quarterback with the Houston Texans of the NFL.
- Seneca Wallace
Seneca Wallace (born August 6, 1980 in Sacramento, California) is an American football quarterback for the NFL's Seattle Seahawks.
- J. J. Moses
J.J. Moses (born September 12, 1979 in Waterloo, Iowa) is an American football wide receiver. His primary roles were as kick returner and punt returner. He also played in the European league, where he was the #1 punt returner for the season. He previously played for the Houston Texans and the Green Bay Packers, mostly on special teams. He was an undrafted free agent out of Iowa State University who played his high school football at Waterloo East High School.
- Oliver Ross
Oliver Ross was born on September 27, 1974 in Culver City, California. He plays for the Arizona Cardinals and is a starting offensive tackle.
- Chris Anthony
Chris Anthony (born January 10, 1979 in Bettendorf, Iowa) is an Arena Football League wide receiver/linebacker for the New York Dragons. He attended Iowa State University.
- Ellis Hobbs
Ellis Hobbs III (born May 16, 1983 in Niagara Falls, New York) is an American football cornerback for the New England Patriots of the National Football League. He was drafted in the third round of the 2005 NFL Draft out of Iowa State University.
- Weylan Harding
Weylan Harding is the current head coach of the New York Dragons of the Arena Football League. At the start of the 2005 season, Harding's first year leading the Dragons, he was 33 years old, making him the second youngest head coach in the history of the league. He had previously worked in the Buffalo Destroyers organization starting in 2000. After the Destroyers moved to Columbus, Ohio he became the team's defensive coordinator in 2002 and returned in 2004.
- James Reed
James Reed (born February 3, 1977 in Saginaw, Michigan) is an American football nose tackle for the NFL's Kansas City Chiefs. The New York Jets drafted him in the seventh round of the 2001 NFL Draft out of Iowa State University. At Iowa State he helped get the Cyclones there first bowl win ever. He played under legendary coach Dan McCarney. On April 17, 2007, Reed was re-signed to the Chiefs with a three-year contract.
- Keith Sims
Keith Sims (born June 17, 1967 in Baltimore, Maryland) was a former American Football player who played offensive line for eleven seasons between 1990 and 2000 for the Miami Dolphins and the Washington Redskins. Sims and Richmond Webb led a top rated offensive line for the Dolphins in the mid-1990s and was a three time Pro Bowler in 1993, 1994 and in 1995. Sims played college football at Iowa State University. Sims played football in High School in Warren, …
- Jordan Carstens
Jordan Lee Carstens (born January 22, 1981 in Carroll, Iowa) is an American football defensive tackle for the NFL's Carolina Panthers. He was an undrafted free agent out of Iowa State University.
- Don Webb
Don Webb (born May 22, 1939 in Jefferson City, Missouri) is a former college and professional American football defensive back. In 1961 he joined the Boston Patriots of the American Football League. He played there for eleven seasons and was a one-time AFL All-Star selection. He was selected to the Patriots All-1960s Decade (AFL) Team
- Tony Yelk
Tony Yelk (born September 29, 1981 in Madison, Wisconsin) is a National Football League punter for the Jacksonville Jaguars, currently listed as the second stringer behind Adam Podlesh. He attended college and played college football at Iowa State University. He was signed by the Jacksonville Jaguars on March 14, 2007 as a free agent.
- Tim Dobbins
Tim Dobbins (born December 10, 1982) is an American football linebacker, who currently plays for the National Football League's San Diego Chargers. He was drafted in round five, pick 151 of the 2006 NFL Draft. Dobbins played college football for the Iowa State University. At Iowa State Dobbins earned all Big 12 honors in his senior season. He led the Cyclones to the Houston Bowl in 2005 and to the Independence Bowl in 2004. He played under legendary coach Dan McCarney.
- Troy Davis
Troy Davis (born September 14, 1975 in Miami, Florida) is a Canadian Football League running back for the Edmonton Eskimos.
- Tony Baker
Tony Baker was a running back in the NFL. He played from 1968, to 1975, and played for the New Orleans Saints, the Philadelphia Eagles, the Los Angeles Rams, and finally, the San Diego Chargers, ending his career with one Pro Bowl appearence in 1968. Born Vernon G. Baker, on February 18, 1945, he graduated from Burlington Community High School in 1961, earning a scolarship to Iowa State University the following year, he would graduate in 1966, …
- Marcus Robertson
Marcus Robertson (born 10/2/1969) is a former defensive back who played from 1991-2002. He played for the Houston Oilers/Tennessee Oilers/Tennessee Titans, and Seattle Seahawks. He attended Iowa State for college.
- Ike Harris
Isiah "Ike" Harris (born November 27, 1952 in West Memphis, Arkansas) is a former American football Wide Receiver for the St. Louis Cardinals (1975-1977) and the New Orleans Saints (1978-1981). He attended Iowa State.
- Jim Doran
Jim Doran (born August 11, 1927 in Boone, Iowa) is a former American football Wide Receiver for the Detroit Lions (1951-1959) and the Dallas Cowboys (1960-1961). He attended Iowa State.
- Ennis Haywood
Ennis Haywood (December 5, 1979 - May 11, 2003) is a former National Football League running back for the Dallas Cowboys, and starred at Iowa State. He was on the Cowboys practice squad in 2002 before competing for a roster spot in 2003. Former running back Emmitt Smith talked about how Ennis always said how he would break all of Emmitt's rushing records someday.
- Reggie Hayward
Reginald Joseph Hayward Jr. (born March 14 1979) is the right defensive end for the Jacksonville Jaguars.
- David Archer
David Archer (born February 15, 1962 in Fayetteville, North Carolina), is a former professional American football player. A 6'2" undrafted quarterback from Iowa State University, Archer played 6 seasons in the NFL from 1984 to 1989 for the Atlanta Falcons, Washington Redskins, San Diego Chargers and Philadelphia Eagles.
- Bob Richardson
Bob Richardson was an award winning Canadian Football League player. Richardson graduated from Iowa State University, where he represented the Cyclones in the 1972 North - South all star games as an offensive lineman, though he could play tight end. In 1972 he went to Canada and played with the Hamilton Tiger-Cats, where he won the Gruen Trophy as the best rookie in the East. He would play there until 1974 and then play 4 more seasons with the Saskatchewan Roughriders, …
- Keith Krepfle
Keith Robert Krepfle (born February 4, 1952 in Dubuque, Iowa), was a former American professional football player who was selected by the Philadelphia Eagles in the 5th round of the 1974 NFL Draft. A 6'4", 240 lbs. tight end from Iowa State University, Krepfle played in 8 NFL seasons from 1975-1982. In 1974 he played with the Jacksonville Sharks of the WFL.
- Dennis Gibson
Dennis Gibson (born February 8, 1964 in Des Moines, Iowa) was a linebacker who played in the National Football League (American football) from 1987-1995 for the Detroit Lions and San Diego Chargers. Perhaps his most memorable moment came in the 1994 AFC Championship game, when he sent the Chargers to the Super Bowl by lunging to block a 4th down-pass attempt from Pittsburgh Steelers quarterback Neil O'Donnell in the endzone to win the game.
- Aaron Brant
Aaron Brant (born September 16, 1984 in Dubuque, Iowa) is an American football Offensive tackle for the Chicago Bears of the NFL. He attended Wahlert High school before playing at Iowa State University.
- Dan Johnson
Dan Johnson (born May 17, 1960 in Minneapolis, Minnesota is a former professional American football player who played tight end for five seasons for the Miami Dolphins.
- Chris Washington
Chris Washington (born March 6, 1962) is a former linebacker in the NFL. He played for the Tampa Bay Buccaneers and Phoenix Cardinals.
- Stan Campbell
Stanley Hugh Campbell (August 26, 1930 - March 14, 2005) was an American collegiate and professional football player. He played professionally for the NFL Detroit Lions and Philadelphia Eagles, and ended his football career with the American Football League's Oakland Raiders in 1962.
- Ozzie Clay
Oswald Clay (born September 10, 1941 in Hickory, North Carolina) was an American football safety in the NFL for the Washington Redskins. He played college football for Iowa State University.
- Mike Stensrud
Mike Stensrud (born February 19, 1956 in Forest City, Iowa) is a former American football defensive lineman who played eleven seasons in the National Football League.
- Gene Williams
Gene Williams (born October 14, 1968) is a former NFL guard who played nine seasons in the NFL from 1991-1999. He started in Super Bowl XXXIII for the Atlanta Falcons.
- Bruce Reimers
Bruce Reimers (born September 18, 1960 in Algona, Iowa) is a former American football guard who played ten seasons with the Cincinnati Bengals and Tampa Bay Buccaneers in the National Football League.