Charles Philip Bednarik (born May 1, 1925 in Bethlehem, Pennsylvania) is a former professional football player, known as one of the most devastating tacklers in the history of football and the last two-way player (excluding Deion Sanders who played offense and defense for the Dallas Cowboys in 1996, he filled in for the suspended Michael Irvin) in the National Football League.

Mark Thomas DeRosa (born February 26, 1975 in Passaic, New Jersey) is a Major League Baseball player who plays for the Chicago Cubs. DeRosa is a utility player and bats right-handed. DeRosa was selected by the Atlanta Braves in the 7th round of the June 1996 free agent draft. DeRosa attended Bergen Catholic High School in New Jersey, with Jim Finn of the New York Giants, where he earned all state honors in baseball and football.

Carroll Rosenbloom (March 5, 1907 - April 2, 1979) was a colorful football owner of two teams, the Baltimore Colts and the Los Angeles Rams, now the St. Louis Rams.

Jim Finn (born December 9, 1976, Fair Lawn, New Jersey) is an American football fullback for the New York Giants NFL franchise. He is currently the national face of Phazyme in their latest ad campaign.

John William Heisman (October 23, 1869 - October 3, 1936) was a prominent American football player and college football coach in the early era of the sport and is the namesake of the Heisman Trophy awarded annually to the season's best college football player.

"Winchester Dana Osgood" was a prominent American college athlete in the late 1800s at both Cornell University and University of Pennsylvania. Osgood volunteered for the Cuban forces during Cuba’s fight for Independence from Spain. He was commissioned a major in artillery in Cuban Army and was killed in combat.

Sol S. Metzger was an American football player and coach. He graduated from the University of Pennsylvania in 1904. Metzger also wrote a nationally syndicated sports column.

DeBenneville (Bert) Bell (February 25, 1895 - October 11, 1959) was co-founder of the Philadelphia Eagles, co-owner and coach of the Pittsburgh Steelers and commissioner of the National Football League from 1946 until his death.

Lou "Luigi Piccolo" Little (1893, Leominster, Massachusetts - May 28 1978, Delray Beach, Florida) was an American football coach.

Brent Howard Novoselsky (born January 8, 1966 in Skokie, Illinois), is a former American professional football player.

Timothy Alan Mazzetti (born February 1, 1956 in Greenwich, Connecticut) is a former NFL kicker from (1978-1980) for the Atlanta Falcons. He later played with the Boston Breakers of the United States Football League.

Alden Arthur Knipe (born 1870, died 1950) was the sixth head football coach at the University of Iowa, coaching from 1898-1902. He was also an author of numerous books for children.

Rob Milanese (born February 25, 1980) is an Arena Football League wide receiver/cornerback for the Philadelphia Soul.

Carl Sheldon "Cap" Williams was an American football player and coach. A Wellington, Ohio native, Williams graduated from the University of Pennsylvania in 1894 with a bachelor of Science and a medical degree in 1897. Williams played both at Oberlin and University of Pennsylvania and coached at the University of Pennsylvania.

James K. "Pat" Dwyer was the head football coach at Louisiana State University for three seasons from 1911 to 1913. He finished his coaching career with an overall record of 16-7-2

Eddie Bell was an American college and professional football player. A halfback, he played college football at the University of Pennsylvania. Professionally, he played for the NFL Philadelphia Eagles from 1955 through 1958, and for the New York Titans of the American Football League in 1960. ya yaya

John H. Outland was an All-American college football player and the namesake of the Outland Trophy. Outland was born in Douglas County, Kansas. After starring in football and baseball at the University of Kansas in 1895 and 1896, Outland went to Philadelphia to complete his medical education. There, he became one of the few men ever to win All-American football honors in both line and the backfield. He was picked by Walter Camp as a tackle for his All-America team in 1897.

Reds Bagnell (September 15, 1928 - July 10, 1995) was an American football halfback in college.

James R. Ludlow "Lud" Wray (b. February 7 1894, Philadelphia, Pennsylvania; d. July 24 1967, Philadelphia) was a professional American football player, coach, and co-founder, with college teammate Bert Bell, of the Philadelphia Eagles of the National Football League. He was the first coach of the Boston Braves (now Washington Redskins) in 1932 and of the Eagles, 1933-1935. His career coaching record was 13-25-3.

Donald Andrew Clune (born August 31, 1952 in Havertown, Pennsylvania) Graduated from Cardinal O'Hara High School and moved onto the University of Pennsylvania where he earned All-American honors in both football and track. Drafted by the New York Giants in 1974. Played 3 seasons in the NFL with the Giants and the Seattle Seahawks. Since 1982 Don has been in private practice for massage therapy in Media, Pennsylvania.

Israel George Levene or Izzy Levene (May 1, 1885 - November 12, 1930) was the head coach of the Tennessee Volunteers football team from 1907 to 1909.